Espiritu Santo Parish, now known as the Archdiocesan Shrine and Parish of Espiritu Santo, is a Roman Catholic parish belonging to the Archdiocese of Manila that is located along Tayuman Street corner Rizal Avenue, Santa Cruz, Manila, Philippines. It was declared an Archdiocesan Shrine by Manila Archbishop Luis Antonio G. Cardinal Tagle on June 8, 2014, the Solemnity of the Pentecost. Rev. Fr. Wilmer R. Rosario, JCD is the present parish priest and rector of the church, succeeding Rev. Msgr. Albert G. Salonga, PC, who has been its parish priest from 1998 to 2015.